The Cover
Treatment of 9L glioma cells with CP248, a derivative of Exisulind (sulindac sulfone), disrupts tubulin polymerization and arrests cells in mitosis. This figure displays an abnormal spindle apparatus in CP248-treated cells. Chromosomal DNA is stained blue; microtubules, green; and MAD2, red. For details, see Yoon et al. in this issue.