Angiogenesis, Metastasis, and the Cellular Microenvironment:

Distinct Functionality of Tumor Cell–Derived Gelatinases during Formation of Liver Metastases

Michael Gerg, Charlotte Kopitz, Susanne Schaten, Alexander Tschukes, Christoph Kahlert, Manfred Stangl, Claus W. Hann von Weyhern, Björn L.D.M. Brücher, Dylan R. Edwards, Karsten Brand, and Achim Krüger
Mol Cancer Res 2008 6: 341-351 doi: 10.1158/1541-7786.MCR-07-2032 [Abstract] [Full Text] [PDF]  

Positive Feedback between Vascular Endothelial Growth Factor-A and Autotaxin in Ovarian Cancer Cells

Malgorzata M. Ptaszynska, Michael L. Pendrak, Russell W. Bandle, Mary L. Stracke, and David D. Roberts
Mol Cancer Res 2008 6: 352-363 doi: 10.1158/1541-7786.MCR-07-0143 [Abstract] [Full Text] [PDF]  

Host Nuclear Factor-B Activation Potentiates Lung Cancer Metastasis

Georgios T. Stathopoulos, Taylor P. Sherrill, Wei Han, Ruxana T. Sadikot, Fiona E. Yull, Timothy S. Blackwell, and Barbara Fingleton
Mol Cancer Res 2008 6: 364-371 doi: 10.1158/1541-7786.MCR-07-0309 [Abstract] [Full Text] [PDF]  

Enhanced Expression of Rab27A Gene by Breast Cancer Cells Promoting Invasiveness and the Metastasis Potential by Secretion of Insulin-Like Growth Factor-II

Jin-Song Wang, Fu-Bin Wang, Qiang-Ge Zhang, Zhen-Zhou Shen, and Zhi-Ming Shao
Mol Cancer Res 2008 6: 372-382 doi: 10.1158/1541-7786.MCR-07-0162 [Abstract] [Full Text] [PDF] Supplementary Data  

Distinct Functions of Natural ADAM-15 Cytoplasmic Domain Variants in Human Mammary Carcinoma

Julia L. Zhong, Zaruhi Poghosyan, Caroline J. Pennington, Xanthe Scott, Madeleine M. Handsley, Alba Warn, Jelena Gavrilovic, Katja Honert, Achim Krüger, Paul N. Span, Fred C.G.J. Sweep, and Dylan R. Edwards
Mol Cancer Res 2008 6: 383-394Published Online First February 22, 2008. doi: 10.1158/1541-7786.MCR-07-2028 [Abstract] [Full Text] [PDF]  

Cancer Genes and Genomics:

Identification of Flotillin-2, a Major Protein on Lipid Rafts, as a Novel Target of p53 Family Members

Yasushi Sasaki, Yuichiro Oshima, Ryota Koyama, Reo Maruyama, Hirofumi Akashi, Hiroaki Mita, Minoru Toyota, Yasuhisa Shinomura, Kohzoh Imai, and Takashi Tokino
Mol Cancer Res 2008 6: 395-406Published Online First February 22, 2008. doi: 10.1158/1541-7786.MCR-07-0108 [Abstract] [Full Text] [PDF]  

Cell Cycle, Cell Death, and Senescence:

Glioma Regression In vitro and In vivo by a Suicide Combined Treatment

Vega García-Escudero, Ricardo Gargini, and Marta Izquierdo
Mol Cancer Res 2008 6: 407-417 doi: 10.1158/1541-7786.MCR-07-0243 [Abstract] [Full Text] [PDF] Supplementary Data  

Binding of the Retinoblastoma Protein Is Not the Determinant for Stable Repression of Some E2F-Regulated Promoters in Muscle Cells

Marie Vandromme, Catherine Chailleux, Fabrice Escaffit, and Didier Trouche
Mol Cancer Res 2008 6: 418-425Published Online First February 22, 2008. doi: 10.1158/1541-7786.MCR-07-0381 [Abstract] [Full Text] [PDF]  

DNA Damage and Cellular Stress Responses:

Epidermal Growth Factor Receptor vIII Expression in U87 Glioblastoma Cells Alters Their Proteasome Composition, Function, and Response to Irradiation

Kwanghee Kim, James M. Brush, Philip A. Watson, Nicholas A. Cacalano, Keisuke S. Iwamoto, and William H. McBride
Mol Cancer Res 2008 6: 426-434 doi: 10.1158/1541-7786.MCR-07-0313 [Abstract] [Full Text] [PDF]  

Signaling and Regulation:

Involvement of Fibroblast Growth Factor Receptor 2 Isoform Switching in Mammary Oncogenesis

Jiyoung Y. Cha, Que T. Lambert, Gary W. Reuther, and Channing J. Der
Mol Cancer Res 2008 6: 435-445 doi: 10.1158/1541-7786.MCR-07-0187 [Abstract] [Full Text] [PDF]  

CXCL12/CXCR4 Transactivates HER2 in Lipid Rafts of Prostate Cancer Cells and Promotes Growth of Metastatic Deposits in Bone

Sreenivasa R. Chinni, Hamilto Yamamoto, Zhong Dong, Aaron Sabbota, R. Daniel Bonfil, and Michael L. Cher
Mol Cancer Res 2008 6: 446-457 doi: 10.1158/1541-7786.MCR-07-0117 [Abstract] [Full Text] [PDF]  

The Critical Role of the Colony-Stimulating Factor-1 Receptor in the Differentiation of Myeloblastic Leukemia Cells

John A. Hamilton, Genevieve Whitty, Paul Masendycz, Nicholas J. Wilson, Jacob Jackson, Dominic De Nardo, and Glen M. Scholz
Mol Cancer Res 2008 6: 458-467 doi: 10.1158/1541-7786.MCR-07-0361 [Abstract] [Full Text] [PDF]  

Modulation of Endocrine Pancreas Development but not β-Cell Carcinogenesis by Sprouty4

Fabienne Jäggi, Miguel A. Cabrita, Anne-Karina T. Perl, and Gerhard Christofori
Mol Cancer Res 2008 6: 468-482 doi: 10.1158/1541-7786.MCR-07-0255 [Abstract] [Full Text] [PDF]  

Metallothionein Induction by Hypoxia Involves Cooperative Interactions between Metal-Responsive Transcription Factor-1 and Hypoxia-Inducible Transcription Factor-1

Brian J. Murphy, Tomoki Kimura, Barbara G. Sato, Yihui Shi, and Glen K. Andrews
Mol Cancer Res 2008 6: 483-490 doi: 10.1158/1541-7786.MCR-07-0341 [Abstract] [Full Text] [PDF] Supplementary Data  

Geldanamycin-Induced Down-Regulation of ErbB2 from the Plasma Membrane Is Clathrin Dependent but Proteasomal Activity Independent

Nina Marie Pedersen, Inger Helene Madshus, Camilla Haslekås, and Espen Stang
Mol Cancer Res 2008 6: 491-500 doi: 10.1158/1541-7786.MCR-07-0191 [Abstract] [Full Text] [PDF] Supplementary Data  

Mitogen-Activated Protein Kinase Kinase 4/c-Jun NH₂-Terminal Kinase Kinase 1 Protein Expression Is Subject to Translational Regulation in Prostate Cancer Cell Lines

Victoria L. Robinson, Ore Shalhav, Kristen Otto, Tomoko Kawai, Myriam Gorospe, and Carrie W. Rinker-Schaeffer
Mol Cancer Res 2008 6: 501-508 doi: 10.1158/1541-7786.MCR-07-2075 [Abstract] [Full Text] [PDF] Supplementary Data  

Cripto-1 Alters Keratinocyte Differentiation via Blockade of Transforming Growth Factor-β1 Signaling: Role in Skin Carcinogenesis

Anjali Shukla, Yan Ho, Xin Liu, Andrew Ryscavage, and Adam B. Glick
Mol Cancer Res 2008 6: 509-516 doi: 10.1158/1541-7786.MCR-07-0396 [Abstract] [Full Text] [PDF]  

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