Subject Reviews:

Systems-Level Analysis of ErbB4 Signaling in Breast Cancer: A Laboratory to Clinical Perspective

Chih-Pin Chuu, Rou-Yu Chen, John L. Barkinge, Mark F. Ciaccio, and Richard B. Jones
Mol Cancer Res 2008 6: 885-891 doi: 10.1158/1541-7786.MCR-07-0369 [Abstract] [Full Text] [PDF]  

Zinc 2-Glycoprotein: A Multidisciplinary Protein

Md. Imtaiyaz Hassan, Abdul Waheed, Savita Yadav, Tej P. Singh, and Faizan Ahmad
Mol Cancer Res 2008 6: 892-906 doi: 10.1158/1541-7786.MCR-07-2195 [Abstract] [Full Text] [PDF]  

Angiogenesis, Metastasis, and the Cellular Microenvironment:

Tumor Environment Dictates Medulloblastoma Cancer Stem Cell Expression and Invasive Phenotype

Borhane Annabi, Shanti Rojas-Sutterlin, Carl Laflamme, Marie-Paule Lachambre, Yannève Rolland, Hervé Sartelet, and Richard Béliveau
Mol Cancer Res 2008 6: 907-916 doi: 10.1158/1541-7786.MCR-07-2184 [Abstract] [Full Text] [PDF]  

Effects of Raf Kinase Inhibitor Protein Expression on Metastasis and Progression of Human Epithelial Ovarian Cancer

Hong Zhao Li, Yue Wang, Yan Gao, Jie Shao, Xiu Lan Zhao, Wei Min Deng, Yi Xin Liu, Jie Yang, and Zhi Yao
Mol Cancer Res 2008 6: 917-928 doi: 10.1158/1541-7786.MCR-08-0093 [Abstract] [Full Text] [PDF]  

Bone Marrow Subsets Differentiate into Endothelial Cells and Pericytes Contributing to Ewing's Tumor Vessels

Krishna Reddy, Zhichao Zhou, Keri Schadler, Shu-Fang Jia, and Eugenie S. Kleinerman
Mol Cancer Res 2008 6: 929-936 doi: 10.1158/1541-7786.MCR-07-2189 [Abstract] [Full Text] [PDF]  

Cancer Genes and Genomics:

Cell Cycle Regulator Gene CDC5L, a Potential Target for 6p12-p21 Amplicon in Osteosarcoma

Xin-Yan Lu, Yaojuan Lu, Yi-Jue Zhao, Kim Jaeweon, Jason Kang, Li Xiao-Nan, Gouqing Ge, Rene Meyer, Laszlo Perlaky, John Hicks, Murali Chintagumpala, Wei-Wen Cai, Marc Ladanyi, Richard Gorlick, Ching C. Lau, Debananda Pati, Michael Sheldon, and Pulivarthi H. Rao
Mol Cancer Res 2008 6: 937-946 doi: 10.1158/1541-7786.MCR-07-2115 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell Cycle, Cell Death, and Senescence:

Mdm2 and Mdm4 Loss Regulates Distinct p53 Activities

Juan A. Barboza, Tomoo Iwakuma, Tamara Terzian, Adel K. El-Naggar, and Guillermina Lozano
Mol Cancer Res 2008 6: 947-954 doi: 10.1158/1541-7786.MCR-07-2079 [Abstract] [Full Text] [PDF]  

G-Quadruplex Stabilizer 3,6-Bis(1-Methyl-4-Vinylpyridinium)Carbazole Diiodide Induces Accelerated Senescence and Inhibits Tumorigenic Properties in Cancer Cells

Fong-Chun Huang, Cheng-Chung Chang, Pei-Jen Lou, I-Chun Kuo, Chih-Wei Chien, Chin-Tin Chen, Fu-Ying Shieh, Ta-Chau Chang, and Jing-Jer Lin
Mol Cancer Res 2008 6: 955-964Published Online First May 30, 2008. doi: 10.1158/1541-7786.MCR-07-0260 [Abstract] [Full Text] [PDF]  

Active Ras Triggers Death in Glioblastoma Cells through Hyperstimulation of Macropinocytosis

Jean H. Overmeyer, Aparna Kaul, Erin E. Johnson, and William A. Maltese
Mol Cancer Res 2008 6: 965-977 doi: 10.1158/1541-7786.MCR-07-2036 [Abstract] [Full Text] [PDF] Supplementary Data  

DNA Damage and Cellular Stress Responses:

Senescence-Dependent MutS Dysfunction Attenuates Mismatch Repair

In-Youb Chang, Ming Jin, Sang Pil Yoon, Cha-Kyung Youn, Young Yoon, Sung-Pyo Moon, Jin-Won Hyun, Jae Yeoul Jun, and Ho Jin You
Mol Cancer Res 2008 6: 978-989 doi: 10.1158/1541-7786.MCR-07-0380 [Abstract] [Full Text] [PDF]  

The RNA Exosome Component hRrp6 Is a Target for 5-Fluorouracil in Human Cells

Susanne Kammler, Søren Lykke-Andersen, and Torben Heick Jensen
Mol Cancer Res 2008 6: 990-995 doi: 10.1158/1541-7786.MCR-07-2217 [Abstract] [Full Text] [PDF]  

Activation of Epidermal Growth Factor Receptor and Its Downstream Signaling Pathway by Nitric Oxide in Response to Ionizing Radiation

Hyung-Chahn Lee, Sungkwan An, Hansoo Lee, Sang-Hyeok Woo, Hyeon-Ok Jin, Sung-Keum Seo, Tae-Boo Choe, Doo-Hyun Yoo, Su-Jae Lee, Young-Joon Hong, Myung-Jin Park, Chang-Hun Rhee, In-Chul Park, and Seok-Il Hong
Mol Cancer Res 2008 6: 996-1002 doi: 10.1158/1541-7786.MCR-08-0113 [Abstract] [Full Text] [PDF] Supplementary Data  

Signaling and Regulation:

Multiple Signaling Pathways Are Responsible for Prostaglandin E₂–Induced Murine Keratinocyte Proliferation

Kausar M. Ansari, Joyce E. Rundhaug, and Susan M. Fischer
Mol Cancer Res 2008 6: 1003-1016 doi: 10.1158/1541-7786.MCR-07-2144 [Abstract] [Full Text] [PDF]  

Secreted Frizzled-Related Protein 4 Regulates Two Wnt7a Signaling Pathways and Inhibits Proliferation in Endometrial Cancer Cells

Kendra S. Carmon and David S. Loose
Mol Cancer Res 2008 6: 1017-1028 doi: 10.1158/1541-7786.MCR-08-0039 [Abstract] [Full Text] [PDF]  

The Effect of Transforming Growth Factor β on Human Neuroendocrine Tumor BON Cell Proliferation and Differentiation Is Mediated through Somatostatin Signaling

Frank P. Leu, Minesh Nandi, and Congrong Niu
Mol Cancer Res 2008 6: 1029-1042 doi: 10.1158/1541-7786.MCR-07-2073 [Abstract] [Full Text] [PDF]  

Prostate-Specific Kallikreins-2 and -4 Enhance the Proliferation of DU-145 Prostate Cancer Cells through Protease-Activated Receptors-1 and -2

Gregory J. Mize, Wenbin Wang, and Thomas K. Takayama
Mol Cancer Res 2008 6: 1043-1051 doi: 10.1158/1541-7786.MCR-08-0096 [Abstract] [Full Text] [PDF]  

A Novel Unidirectional Cross-Talk from the Insulin-Like Growth Factor-I Receptor to Leptin Receptor in Human Breast Cancer Cells

Tuba Ozbay and Rita Nahta
Mol Cancer Res 2008 6: 1052-1058Published Online First May 30, 2008. doi: 10.1158/1541-7786.MCR-07-2126 [Abstract] [Full Text] [PDF]  

Targeting Nuclear Factor-B Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

Gautam Sethi, Kwang Seok Ahn, and Bharat B. Aggarwal
Mol Cancer Res 2008 6: 1059-1070 doi: 10.1158/1541-7786.MCR-07-2088 [Abstract] [Full Text] [PDF]  

TATA Box-Binding Protein–Associated Factor 12 Is Important for RAS-Induced Transformation Properties of Colorectal Cancer Cells

Angeliki Voulgari, Stella Voskou, Làszlò Tora, Irwin Davidson, Takehiko Sasazuki, Senji Shirasawa, and Alexander Pintzas
Mol Cancer Res 2008 6: 1071-1083 doi: 10.1158/1541-7786.MCR-07-0375 [Abstract] [Full Text] [PDF]  

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